Big Data for Medication Safety and Pharmacoeconomics

Pharmacoepidemiology & pharmacoeconomics

• Population-based studies of drug safety and effectiveness to advance medication practice and pharmacoepidemiology research.
• Development of methodologies to predict future risk of cardiovascular events and adverse drug reactions using big data from population databases.
• Evaluation of the effectiveness and safety of medications used in the elderly, children, pregnancy and other special patient groups.
• Safety and effectiveness of cardiovascular drugs (e.g., anticoagulants, statins, aspirin) and effects on bone, liver, kidney and cancer.
• Post-marketing surveillance of safety of medications used in the management of respiratory disorders, psychiatric disorders and infectious diseases.
• Pharmacoeconomics of pharmacotherapy in chronic illness and public health interventions – determination of healthcare resource utilisation; analyses of oral anticoagulants, vaccinations, drug use in rare diseases using the willingness-to-pay concept, decision-analytic models and budget impact models.

Clinical trials and practice-based research:

• Design of interventional clinical trials to compare the effectiveness and safety of drugs used in the emergency setting for sedation, epilepsy and pain control.
• Clinical and pharmacy practice-based research to characterise drug-related problems and pharmacists' clinical intervention.
• Assessment of the appropriateness of medications in the older population.