Department of Pharmacology and Pharmacy, The University of Hong Kong

Research in Department

Our research is highly interdisciplinary with a dynamic research profile, which spans from basic pharmacology and drug development, through drug delivery and formulation, to clinical trials and big data research, use of medicines by patients and safe medication practice. Our researchers work closely together towards the common goal of developing new medicines and formulations that can be evaluated in patients, improving health and quality of life.

 

Highlighted Publications
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Adiponectin-expressing Treg facilitate T lymphocyte development in thymic nurse cell complexes

Yiwei Zhang, Handi Cao, Jie Chen, Yuanxin Li, Aimin Xu, Yu Wang

Nature. https://doi.org/10.1038/s42003-021-01877-w

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A Red Light‐Triggered Drug Release System Based on One‐Photon Upconversion‐Like Photolysis

Wen Lv,  Kaiqi Long,  Yang Yang,  Sijie Chen,  Changyou Zhan,  Weiping Wang

Advanced Healthcare Materials. https://doi.org/10.1002/adhm.202001118

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Gut Microbiota-Associated Activation of TLR5 Induces Apolipoprotein A1 Production in the Liver

Jensen Ho Cheung Yiu, Kam-Suen Chan, Jamie Cheung, Jin Li, Yan Liu, Yao Wang, Wai Lun William Fung, Jieling Cai, Samson WM Cheung, Bernhard Dorweiler, Eric Yuk Fai Wan, Patrick Tso, Aimin Xu, and Connie Wai Hong Woo

Circulation Research (2020). https://doi.org/10.1161/CIRCRESAHA.120.317362

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Adipocyte fatty acid-binding protein exacerbates cerebral ischaemia injury by disrupting the blood–brain barrier

Boya Liao, Leiluo Geng, Fang Zhang, Lingling Shu, Ling Wei, Patrick K K Yeung, Karen S L Lam, Sookja K Chung, Junlei Chang, Paul M Vanhoutte, Aimin Xu, Kai Wang, Ruby L C Hoo

European Heart Journal (2020), ehaa207, https://doi.org/10.1093/eurheartj/ehaa207

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Effective mRNA pulmonary delivery by dry powder formulation of PEGylated synthetic KL4 peptide

Yingshan Qiu, Rico CH Man, Qiuying Liao, Keshia LK Kung, Michael YT Chow , Jenny KW Lam

Journal of Controlled Release (2019). 314: 102-114

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Upconversion-like Photolysis of BIODIPY-Based Prodrugs via a One-Photon Process

Wen Lv, Yafei Li, Feiyang Li, Xin Lan, Yaming Zhang, Lili Du, Qiang Zhao, David Philips, Weiping Wang

Journal of the American Chemical Society (2019). 141, 44, 17482-17486

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Assessment of Vascular Tone Responsiveness using Isolated Mesenteric Arteries with a Focus on Modulation by Perivascular Adipose Tissues

Daniels Konja, Cuiting Luo, Wai Yan Sun, Kangmin Yang, Andy W.C. Man, Aimin Xu, Paul M. Vanhoutte, Yu Wang

Journal of Visualized Experiments (2019). 148: e59688

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Endothelial SIRT1 prevents age-induced impairment of vasodilator responses by enhancing the expression and activity of soluble guanylyl cyclase in smooth muscle cells

Yumeng Guo, Cheng Xu, Andy W C Man, Bo Bai, Cuiting Luo, Yu Huang, Aimin Xu, Paul M Vanhoutte, Yu Wang.

Cardiovascular Research (2019). 115(3): 678-690

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