Dr Ng obtained his BSc degree in Chemistry from Imperial College London (funded by Macau Government Special Scholarship) with Departmental Prize of Organic Chemistry, and his PhD degree from The University of Hong Kong.

After graduation, he first pursued a postdoc in organic synthesis in Prof Pauline Chiu’s group (HKU and SUSTech), during which he developed new organometallic reactions. After years of research in organic synthesis, he brought his experience to a different field of research, pursuing computational chemistry in Prof Hajime Hirao’s group (CUHK-SZ), during which he studied reaction mechanisms by computational methods.

In addition to his focus on chemistry, he maintains a strong interest in technology. He represented Macau SAR at the 39th WorldSkills International Competition (in Shizuoka, Japan), also known as the ‘Olympics’ of vocational skills, where he received a Medallion for Excellence in IT/Software Application.

He joined the Department of Pharmacology and Pharmacy in 2023. Currently he is an assistant lecturer in the department. He has an active interest in developing GenAI powered application for teaching and learning. He is also having active research collaborations with different universities to elucidate new reaction mechanisms by computational methods.

Platform for virtual learning: www.ai-for-pharmacists.com

AI studio: www.ai-for-students.com

(Teachers are welcome to contact him to obtain guest access)

Honours and Awards

Medallion for Excellence, in IT/Software Applications (39^th WorldSkills International Competition, Shizuoka, Japan, 2007)

• The “Olympic Game” of vocational skills, between 85 countries/regions

• Development of GenAI powered learning platforms (www.ai-for-pharmacists.com)
• Application of computational chemistry to understand reaction mechanism

Selected Publications

CHEMICAL EDUCATION

• Wong, K.-C.*;  Ip, I.; Ng, E. W. H., Enhancing Stereochemistry Education through Inquiry-Based Learning and Concrete Molecular Models. J. Chem. Educ. 2025, 102 (2), 583-592. (I.F.= 2.5)

COMPUTATIONAL CHEMISTRY

• Li, S.; Gong, Q.-W.; Lam, Y. T. C.; Ng, E. W. H.*; Song, J.*; Gong, L.-Z.* Remote Enantioselective Redox ε-Alkylation of Copper Allylic Allenylidenes with Enals. Angew. Chem. Int. Ed. 2025, e202519335. (I.F.= 16.9)
• Zheng, Y.;  NG, E. W. H.;  Rizzo, A.; Chiu, P., Enantiomerically Enriched Aziridine-2-carboxylates via Copper-Catalyzed Reductive Kinetic Resolution of 2H-Azirines. Angew. Chem. Int. Ed., 2025, e202423645. (I.F.= 16.9)
• Yue, D.; Ng, E. W. H.; Hirao, H.*, Hydrogen-Bond-Assisted Catalysis: Hydroxylation of Paclitaxel by Human CYP2C8, J. Am. Chem. Soc., 2024, 146 (44), 30117-30125. (I.F.= 14.5)
• Lee, Y.;  Kim, B.;  Kim, S.;  Ng, E. W. H.;  Ariyasu, S.;  Shoji, O.;  Yoon, S.;  Hirao, H.; Cho, J., Influence of Solvents on Catalytic C–H Bond Oxidation by a Copper(II)–Alkylperoxo Complex. ACS Catal., 2024, 14 (5), 3524-3532. (I.F.= 11.7)
• (co-first author) Jin, Y.; Fan, L-F; Ng, E. W. H.; Yu, Lu; Hirao, H.*; Gong, L.Z.*, Atom Transfer Radical Coupling Enables Highly Enantioselective Carbo-Oxygenation of Alkenes with Hydrocarbons, J. Am. Chem. Soc., 2023, 145 (40), 22031–22040. (I.F.= 14.5)
• Teng, S.; Ng, E. W. H.; Zhang, Z.; Soon, C.N.; Xu, H.; Li, R.; Hirao, H.*; Loh, T-P*, Alkynone β-trifluoroborates: a new class of amine-specific biocompatible click reagents. Sci. Adv., 2023, 9 (17), eadg4924. (I.F.= 14.1)
• Nilouyal, S.; Karahan, H. E.; Ng, E. W. H.; Yamaguchi, D.; Ito, M. M. M.; Qin, D.; Hirao, H.; Sivaniah, E.*; Ghalei, B.*, Nanobiomineralization of Carbon Dioxide by Molecularly Engineered Metal−Histidine Complex Nanozymes. Chem. Mater. 2023, 35 (4), 1610–1623. (I.F.= 7.2)
• (co-first author) Xi, J.; Ng, E. W. H.; Ho, C.-Y.*, Unsymmetric N-Aryl Substituent Effects on Chiral NHC-Cu: Enantioselectivity and Reactivity Enhancement by Ortho-H and Syn-Configuration. ACS Catal. 2023, 13 (1), 407–421. (I.F.= 11.7)
• (co-first author) Jin, Y., Ng, E.W.H., Fan, T., Hirao, H.*, Gong, L.Z., Photochemical Allylation of Alkanes Enabled by Nickel Catalysis, ACS Catal. 2022, 12 (16), 10039–10046. (I.F.= 11.7)
• Yong, X., Ng, E.W.H., Zhen, Z., Lin, X., Gao, W., Ho, C.*, NHC‐Ni(0) catalyzed diastereodivergent hydroacylative enyne cyclization: synthesis of heterocycles bearing γ‐enone. Adv. Synth. Catal. 2020, 362 (19), 4164–4172. (I.F.= 4.4)

ORGANIC SYNTHESIS

• Ng, E. W. H.; Low, K-H+, Chiu, P.*, Synthesis and Applications of Unquaternized C-Bound Boron Enolates. J. Am. Chem. Soc. 2018, 140(10), 3537-3541 (Highlighted in Organic Process Research & Development) (I.F.= 14.5)
• (co-first author) Wong, K. C.; Ng, E.; Wong, W.-T.+; Chiu, P.*, Copper Hydride Catalyzed Reductive Claisen Rearrangements. Chem. Eur. J. 2016, 22 (11), 3709-3712 (I.F.= 3.9)
• Pisaneschi, F.; Sejberg, J. J. P.; Blain, C.; Ng, W. H.; Aboagye, E. O.; Spivey, A. C.*, 2-Substituted-2,3-dihydro-1H-quinolin-4-ones via Acid-Catalyzed Tandem Rupe Rearrangement-Donnelly-Farrell Ring Closure of 2-(3′-Hydroxy­propynyl)anilines. Synlett 2011, 2011 (02), 241-244 (I.F.= 1.7)