Prof. Zhou was jointly appointed by School of Public Health and Department of Pharmacology and Pharmacy at the University of Hong Kong (HKU) Li Ka Shing Faculty of Medicine in 2024. Prof. Zhou received his post-doctoral training as a Medical Statistician at the Nuffield Department of Clinical Medicine, University of Oxford, United Kingdom. He earned his Ph.D. in Data Science from School of Data Science, City University of Hong Kong, Hong Kong SAR, China. Before joining HKU, Prof. Zhou worked as Assistant Professor at Warwick Medical School, University of Warwick, United Kingdom.

Prof Zhou has research interests in big data analytics, medical statistics, primary care and preventive health, case-control and cohort studies, predictive and decision analytics, pharmacoepidemiology and aetiology of chronic diseases (including cardiovascular diseases, diabetes mellitus, etc. for family medicine patients). He also has study interests in casual treatment effects analysis (double machine learning), social epidemiology and adverse online events identification with text mining, high-dimension data representation and latent cluster pattern learning in large-scale health datasets. Recently, he is conducting personalized Artificial Intelligence and interpretable machine learning analytics for illness trajectories and palliative care, especially risk progression pattern analysis/visualization, end-stage disease risk assessment following chronic/infection diseases, and individualized non-invasive cancer screening, diagnosis and management tools.

Honours and Awards

• 2014 Outstanding Undergraduate Thesis, BIT
• 2016 National Scholarship for Graduate Students, China Education Ministry
• 2017 Outstanding Postgraduate Thesis/Triple A Student, BUCT
• 2018 Postgraduate Studentship for Ph.D. study, RGC of Hong Kong S.A.R.
• 2018 Champion Award in Opioid Data Analytics Hackathon, UCLA, US.
• 2019 UGC Research Travel Grant

Key Research Area:

• Medical statistics, case-control study designs, population cohort studies, casual effects analysis (propensity score matching, inverse probability weighting, Bayesian modeling, double machine learning), and cost-effectiveness analysis.
• Health big data analytics for primary care of communicable and non-communicable diseases, including COVID-19, liver diseases, cardiovascular diseases, diabetes, hypertension, and renal failure.
• Personalized AI for illness trajectories and palliative care modeling, by identifying and visualizing patient risk progression patterns, severe follow-up risk assessment, and developing individualized non-invasive cancer screening, diagnosis and management tools.
• Multi-antibiotics resistance prediction with patient clinical characteristics, blood culture and sensitivity tests using interpretable machine learning.

Selected Publications

• Jiandong Zhou, Xiansong Wang, Sharen Lee, William Ka Kei Wu, Bernard Man Yung Cheung, Qingpeng Zhang, Gary Tse. Proton pump inhibitor or famotidine use and severe COVID-19 disease: a propensity score-matched territory-wide study. Gut (IF: 31.793) 2020 Nov 70(10); 2012-2013. Doi: 10.1136/gutjnl-2020-323668.
• Jiandong Zhou, Sharen Lee, Xiansong Wang, Yi Li, William Ka Kei Wu, Tong Liu, Zhidong Cao, Daniel Dajun Zeng, Keith Sai Kit Leung, Abraham Ka Chung Wai, Ian Chi Kei Wong, Bernard Man Yung Cheung, Qingpeng Zhang, Gary Tse. Development of A Multivariable Prediction Model for Severe COVID-19 Disease: A Population-Based Study from Hong Kong. NPJ Digital Medicine (IF: 15.2), 2021, 4(1): 66, Doi: 10.1038/s41746-021-00433-4.
• Oscar Hou In Chou, Jing Ning, Raymond Ngai Chiu Chan, Cheuk To Chung, Helen Huang, Kenrick Ng, Edward Christopher Dee, Sharen Lee, Apichat Kaewdech, Ariel K Man Chow, Nancy Kwan Man, Tong Liu, Fengshi Jing, Bernard Man Yung Cheung, Gary Tse, Jiandong Zhou*. Lower Risks of New-Onset Hepatocellular Carcinoma in Patients with Type 2 Diabetes Mellitus Treated With SGLT2 Inhibitors Versus DPP4 Inhibitors. Journal of the National Comprehensive Cancer Network (IF: 14.8) 2024 May, 22(2D). Doi: 10.6004/jnccn.2023.7118.
• Oscar Hou In Chou, Vinod Kumar Chauhan, Cheuk To Skylar Chung, Lei Lu, Teddy Tai Loy Lee, Zita Man Wai Ng, Karin Kai Wing Wang, Sharen Lee, Haipeng Liu, Ronald Ting Kai Pang, Apichat Kaewdech, Bernard Man Yung Cheung, Gary Tse, Jiandong Zhou*. Comparative effectiveness of sodium-glucose cotransporter-2 inhibitors for new-onset gastric cancer and gastric diseases in patients with type 2 diabetes mellitus: a population-based cohort study. Gastric Cancer (IF: 6.6) 2024 June 1-24. Doi: 10.1007/s10120-024-01512-7.
• Yan Hiu Athena Lee, Jiandong Zhou (Co-first author), Jeremy Man Ho Hui, Xuejin Liu, Teddy Tai Loy Lee, Kyle Hui, Jeffrey Shi Kai Chan, Abraham Ka Chung Wai, Wing Tak Wong, Tong Liu, Kenrick Ng, Sharen Lee, Edward Christopher Dee, Qingpeng Zhang, Gary Tse. Risk of New-Onset Prostate Cancer for Metformin Versus Sulfonylurea Use in Type 2 Diabetes Mellitus: A Propensity Score–Matched Study. Journal of the National Comprehensive Cancer Network (IF: 14.8) 2022 July, 20(6), 674-682. Doi: 10.6004/jnccn.2022.7010.
• Oscar Hou In Chou, Lei Lu, Cheuk To Chung, Jeffrey Shi Kai Chan, Raymond Ngai Chiu Chan, Athena Yan Hiu Lee, Edward Christopher Dee, Kenrick Ng, Hugo Hok Him Pui, Sharen Lee, Bernard Man Yung Cheung, Gary Tse, Jiandong Zhou*. Diabetes & Metabolism (IF: 6.5). 2024 Aug (Just accepted and to appear).
• Xinyi Gao, Nan Zhang, Lei Lu, Tianyu Gao, Oscar Hou In Chou, Wing Tak Wong, Carlin Chang, Abraham Ka Chung Wai, Gregory Y. H. Lip, Qingpeng Zhang, Gary Tse, Tong Liu, Jiandong Zhou*. New-Onset Syncope in Diabetic Patients Treated with Sodium-Glucose Cotransporter-2 Inhibitors Versus Dipeptidyl Peptidase-4 Inhibitors: A Chinese Population-Based Cohort Study. European Heart Journal - Cardiovascular Pharmacotherapy (IF: 5.3), 2023. Doi: 10.1093/ehjcvp/pvad086.
• Chung Cheuk To, Lakhani Ishan, Chou Oscar, Lee Teddy, Dee Edward, Ng Kendrick, Wong Wing, Liu Tong, Lee Sharen, Cheung Bernard, Zhang Qingpeng, Tse Gary, Zhou Jiandong*. Clinical Characteristics, Risk Factors and Outcomes of Cancer Patients With COVID-19: A Population-Based Study. Cancer Medicine (IF: 4.5), 2023, 12(1): 287-296. Doi: 10.1002/cam4.4888.
• Jiandong Zhou, Sharen Lee, Wing Tak Wong, Khalid Bin Waleed, Keith Sai Kit Leung, Teddy Tai Loy Lee, Abraham Ka Chung Wai, Tong Liu, Carlin Chang, Bernard Man Yung Cheung, Qingpeng Zhang, Gary Tse. Gender-Specific Clinical Risk Scores Incorporating Blood Pressure Variability for Predicting Incident Dementia. Journal of the American Medical Informatics Association (IF: 7.942), 2022, 29(2): 335-347. Doi: 10.1136/gutjnl-2020-323668.
• Jeffrey Shi Kai Chan, Danish Iltaf Satti, Yan Hiu Athena Lee, Jeremy Man Ho Hui, Teddy Tai Loy Lee, Oscar Hou In Chou, Abraham Ka Chung Wai, Ana Ciobanu, Ying Liu, Tong Liu, Leonardo Roever, Giuseppe Biondi-Zoccai, Qingpeng Zhang, Bernard Man Yung Cheung, Jiandong Zhou*, Gary Tse*. High Visit-to-Visit Cholesterol Variability Predicts Heart Failure and Adverse Cardiovascular Events: A Population-Based Cohort Study, European Journal of Preventive Cardiology (IF: 8.4), 2022, 29(14), e323-e325. Doi: 10.1093/eurjpc/zwac097.

Invited talks:

• Nov 22-24, 2024, Transplantation Science Symposium Asian Regional Meeting (Shanghai, China) “Personalised Artificial Intelligence for Liver Health Management: Progress and Challenges”
• Aug 25-28,2024 , The 18th Congress of Asian Society of Transplantation (Hong Kong, China) “Machine learning model development - The view from data scientist”

Professional Experiences:

• Editoral Board Member for Medicine Advances (ISSN:2834-4405)
• Editoral Board Member for Data Science and Management (ISSN: 2666-7649)