Dr. Alan Worsley
Principal Lecturer
Dr. Alan Worsley
Department of Pharmacology and Pharmacy
The University of Hong Kong
HKU Hubs
Email
The University of Hong Kong
L.K.S. Faculty of Medicine Building
Office:
2/F, 21 Sassoon Road, Li Ka Shing Faculty of Medicine,
Laboratory Block, Faculty of Medicine Building,
Hong Kong SAR, China.

Director of Teaching and Learning
Principal Lecturer

Dr. Alan Worsley (禾思理)
BSc, MSc, PhD, Cert Ed (HE)

Memberships:

  • Member of the Royal Society of Chemistry (MRSC)
  • Member of the European Phytochemical Society
  • Member of the GPhC (GPhC)
  • Member of Institute for Learning (MILT)

My Research Interests

  • Metabolic activation and drug toxicity- structural alerts. Consequences upon idiosyncratic drug toxicities
  • Teratological evaluation of traditional Chinese medicine and conventional therapies in S.E.Asian population
  • Toxic principles of native Strophanthus, Nerium and Cerbera species

Selected Publications

  • He, Y, Wong, AYS, Chan, EWY, Lau, WCY, Man, KKC, Chui, CSL, Worsley, AJ, Wong, ICK. Safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis. International Society of Pharmacovigilance XIII Meeting, Pisa, Italy, 1-4 October 2013 & International Society for Pharmacoepidemiology (ISPE) 8th Asian Conference on Pharmacoepidemiology, Hong Kong, China, 25-27 October 2013
  • Hsu, WWQ, Sing, CW, He, Y, Worsley, AJ, Wong, ICK, Chan, EWY. Systematic Review and Meta-Analysis of the Efficacy and Safety of Perampanel in the Treatment of Partial-Onset Epilepsy. CNS drugs, 2013, v 27(10), p. 817-827.
  • Dufay, S, Worsley, AJ, Monteillier, A, Avanzi, C, Sy, LK, Ng, TF, Garcia, JM, Lam, MF, Vanhoutte, PMGR, Wong, ICK. Herbal tea extracts inhibit Cytochrome P450 3A4 in vitro. Journal of Pharmacy and Pharmacology, 2014, v. 66, p. 1478-1490.
  • Antibacterial Agents: Chemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications. Anderson. R., Groundwater. P., Todd. A., Worsley. A. Wiley Ltd 2012. ISBN-10: 0470972459
  • Todd A, Husband A, Worsley A. Role of the hedgehog pathway in cancer pathogenesis. Med Ther 2011; 58 : 33-35.
  • Groundwater P, Todd A, Worsley A J, Anderson A. The technology and techniques used in the detection of pathogenic bacteria. Pharm J, 2009; 283: 281-282.
  • Baqir W, Smith S & Worsley A. Reducing benzodiazepine use: And evaluation of a simple letter intervention. Int J Pharm Pract. 2009; (suppl) 1 : A27
  • Guntupalli C, Worsley A, Groundwater PG, Anderson R J, Lough P, Satyanaya D. Antioxidant activity of methanolic leaf extract of Tetractomia roxburghiana (family rutaceae). Journal Pharm Pharmacol. 2005; 57: 154.
  • Al-Hiari, Y.M., Bennett, S.J., Cox, B., Davies, R.J., Khalaf, A.I., Waigh, R.D., Worsley, A.J. Steps Towards A Practical Synthesis Of Macrocyclic Bisbenzylisoquinolines, Journal Of Heterocyclic Chemistry, 2005, v. 42 n. 4, p.647-659
  • Collins NB, Beard RJ, Candlish C & Worsley AJ. Osteoporosis assessment tool for City Hospitals. Int J Pharm Pract. 2002;10 (suppl): R24
  • Seymour HE, Worsley A, Smith JM, et al. Anti-TNF agents for rheumatoid arthritis. Brit J Clin Pharmacol. 2001; 51 (3): 201-208
  • Therapeutics in Drugs and pregnancy. Chapter 10. Worsley AJ, Psychiatric Disorders. Lee.A. (Editor). Radcliffe Press Ltd. 2000.
  • McElhatton PR, Bateman DN, Evans C, Worsley AJ. The outcome of pregnancy following iron overdose by the mother. B J Clin Pharmacol 1998;45: 212
  • McElhatton PR, Bateman DN, Evans C, Worsley AJ. Does Prenatal exposure to ecstasy cause congenital malformations?. B J Clin Pharmacol 1998;45:183