Dr. C.W. SING 成楚頴
Biography
Dr. Wing Sing obtained her PhD in pharmacogenetics and pharmacoepidemiology at the University of Hong Kong (HKU). She received post-doctoral training in the Department of Pharmacology and Pharmacy, HKU, under the supervision of Dr. Ching-Lung Cheung. In 2022, she is jointly appointed as Research Assistant Professor by the Department of Pharmacology and Pharmacy, Department of Paediatrics & Adolescent Medicine, and Department of Social Work and Social Administration at HKU.
Dr Sing’s research work focused on the epidemiology and pharmacoepidemiology of bone-related diseases and endocrine disorders. She is interested in the safety and repurposing of medications for treatment of osteoporosis and diabetes, particularly in the oldest old population. Her expertise is in big data research using various healthcare databases.
Editorships
- Review editor for Advanced Methods in Pharmacovigilance and Pharmacoepiemiology
Research Interests
- Epidemiology and Pharmacoepidemiology using big data
- Safety and drug repurposing of medications for treatment of osteoporosis and diabetes
- Comorbidity and pharmacoepidemiology in oldest old population
Publications
Selected Publications
- Sing CW, Tang CTL, Chui CSL, Fan M, Lai FTT, Li X, Wan EYF, Wong CKH, Chan EWY, Hung IFN, Leung AY, Cheung CL, Wong ICK. COVID-19 vaccines and risks of hematological abnormalities: nested case-control and self-controlled case series study. Am J Hematol. 2022 Jan 26.(IF 10.05)
- Sing CW*, Cheung CL* (*co-first author), Lau WC, Li GHY, Tan KCB, Cheung BMY, Chan EW, Li SX, Lip GYH, Wong ICK. Treatment with direct oral anticoagulants or warfarin and the risk for incident diabetes among patients with atrial fibrillation: a population‐based cohort study. Cardiovasc Diabetol. 20, 71 (2021) (IF 9.951)
- Sing CW, Lin TC, Bartholomew S, Bell JS, Bennett C, Beyene K, et al. Global burden of hip fractures – trends in incidence, post-fracture treatment, and mortality; a study protocol for a multi-country, observational study. BMJ Open 2021;11:e047258. (IF 2.692)
- Sing CW, Tan KCB, Wong ICK, Cheung BMY, Cheung CL. Long-term outcome of short-course high-dose glucocorticoids for SARS: a 17-year follow-up in SARS survivors. Clin Infect Dis. 2020;ciaa992. doi:10.1093/cid/ciaa992 (IF 9.079)
- Sing CW, Kiel DP, Hubbard RB, Lau CY, Li GHY, Kung AWC, Wong ICK, Cheung CL. Nitrogen‐Containing Bisphosphonates Are Associated With Reduced Risk of Pneumonia in Patients With Hip Fracture. J Bone Miner Res. 2020 June 2. doi: 10.1002/jbmr.4030 (IF 6.741)
- Sing CW*, Lam MT* (*co-first authors), Li GHY, Kung AWC, Tan KCB, Cheung CL. Development and Validation of a Risk Score to Predict the First Hip Fracture in the Oldest Old: A Retrospective Cohort Study. J Gerontol A Biol Sci Med Sci. 2019 Jul 29. pii: glz178. doi: 10.1093/gerona/glz178. (IF 6.053)
- Sing CW, Wong AY, Kiel DP, Cheung EY, Lam JK, Cheung TT et al. Association of Alendronate and Risk of Cardiovascular Events in Patients with Hip Fracture. J Bone Miner Res. 2018 May 9 (IF 5.854)
- Lau WC, Chan EW, Cheung CL, Sing CW, Man KK, Lip GY et al. Association Between Dabigatran vs Warfarin and Risk of Osteoporotic Fractures Among Patients With Nonvalvular Atrial Fibrillation. JAMA. 2017 Mar;317(11):1151-1158. (IF 45.540)
- Sing CW, Cheng VK, Ho DK, Kung AW, Cheung BM, Wong IC et al. Serum calcium and incident diabetes: an observational study and meta-analysis. Osteoporos Int. 2016 May;27(5):1747-54. (IF 3.864)
- Cheung CL, Sing CW, Tang CS, Cheng VK, Pirmohamed M, Choi CH et al. HLA-B*38:02:01 predicts carbimazole/methimazole-induced agranulocytosis. Clin Pharmacol Ther. 2016 May;99(5):555-61. (IF 6.565)
Funding
- Health and Medical Research Fund 2019/2020 “Is the use of bisphosphonates associated with lower risk of dementia? A real-world pharmacoepidemiology study in Hong Kong and the United Kingdom.” (18192451) (HKD 555,896 for 2 years, PI)