Our contribution to the prevention and treatment of COVID-19

 

As healthcare professionals, pharmacists play a key role in the pandemic. Our department has significant contribution to the education, practice and research in COVID-19 and vaccine.

 

 

  

Immunisation Training Programme for Registered Pharmacists


Education in Vaccination

To facilitate the operation of vaccination programme and the education of current and future pharmacists in Hong Kong, our department has partnered with other professional institutes and organisations to provide various vaccination training programmes.

 

Vaccine injection
The programs

 

Online Training Programme for the Reconstitution of Fosun/BioNTech COVID-19 Vaccine Programme

 

Immunisation Training Programme for Registered Pharmacists

 

Immunisation Workshop for BPharm Students 

 

 

  

Immunisation Training Programme for Undergraduate Students


Photos
Immunisation Training Programme

Immunisation Training Programme


Immunisation Workshop for BPharm Students

Immunisation Workshop for BPharm Students



Practice in Vaccination Centre

HKUMed is responsible for the Community Vaccination Centre at Ap Lei Chau Sports Centre (ALC CVC). Pharmacists from our department and our alumni help to prepare and dilute the vaccines on site.

 

CVC Center
The ALC CVC

The Community Vaccination Centre at Ap Lei Chau Sports Centre (ALC CVC)

Photos
ALC CVC Center

ALC CVC Center


The HKU Pharmacist Team

The HKU Pharmacist Team


Vaccination Booths

Vaccination Booths


Preparation Area

Preparation Area



Research related to COVID-19 and Vaccine

Our department is actively involved in research with COVID-19 and vaccines. We have a number of projects funded by the government to improve our understanding of the disease and the impact of the new vaccines, and the development of new medication to fight against the virus.

 

Research for COVID-19
Projects

COVID-19 Vaccines Adverse Effects Response & Evaluation (CARE) 

Care Program

Click to watch


A multinational big data Covid-19 Epidemiological Study on post infection Outcomes (ACESO)

  • This is a multinational study with collaborations from USA, Australia, UK, Taiwan, Korea, Finland and Netherlands to investigate the long-term outcomes of COVID-19 on individual patient as well as on population as a whole. 
    Principal Investigator: Professor Ian Wong, Funding: HK$9,691,060


Effectiveness of single and combined anti-COVID-19 drugs among hospitalized COVID-19 patients in Hong Kong

  • The objective of this study is to evaluate the effectiveness of single and combined antiviral therapies in treating hospitalized patients confirmed with COVID-19 infection in Hong Kong, measure potential effects of adjunctive drugs, and assess post-discharge adverse events among COVID-19 patients. 
    Principal Investigator: Dr. Carlos Wong, Funding: HK$482,960


The role of smoking on the regulation of ACE2-mediated infectability of COVID-19

  • The broad goal of this research is to exploit how the expression of angiotensin-converting enzyme 2 (ACE2) is regulated in airway epithelia under smoking in vitro and in vivo before and after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Emphasis will be placed on its roles in viral replication and renin-angiotensin system (RAS) in relation to disease severity. 
    Principal Investigator: Dr. Judith Mak, Funding: HK$1,997,000


Photos
CARE Programme

CARE Programme


New Medication Development

New Medication Development


Our Researcher

Our Researcher


Big Data Research

Big Data Research



Knowledge Exchange related to COVID-19 and Vaccine
 
Knowledge Exchange
Media

  • 明報 - 副刊健康版 [疫苗有空氣會攞命? 肌肉注射 不會氣泡栓塞] | View

新冠疫苗上月開打,大家捲起衫袖露出上臂接種。港大微生物學系講座教授袁國勇卻自行在前臂打針,還說:「呢個皮內注射,好痛㗎,不過正嘢嚟。」疫苗接種方式一般分為肌肉、皮下、皮內注射3種,究竟有何分別?

  • 香港電台香港家書 [新冠疫苗副作用受嚴謹機制監察] | View

香港大學藥理及藥劑學系系主任黃志基

  • 冠狀病毒病疫苗安全監測計劃 CARE Programme | View

2019 冠狀病毒病是影響人們健康和生活的全球大流行的病毒。2019冠狀病毒病疫苗預計將在控制全球大流行中發揮重要作用。因此,在香港市民開始接種2019冠狀病毒病疫苗的同時,密切監測疫苗的安全性至關重要。全面的疫苗上巿後監測機制可以觀察到疫苗廣泛使用後的潛在異常事件。 香港大學2019冠狀病毒病疫苗安全監測計劃(CARE)是一套完善的2019冠狀病毒病疫苗安全監測機制,嚴密監測各類2019冠狀病毒疫苗已知及潛在的的異常事件,確定所有異常事件的詳細信息,並將這一監測結果及時向社會公眾公佈。此監測計劃是由香港大學藥理及藥劑學系團隊負責實行。 研究團隊誠邀首批優先接種2019冠狀病毒病疫苗的人士積極參與研究計劃, 協助研究團隊吸取經驗, 推展日後疫苗接種, 齊心打贏抗疫戰。


Publications related to COVID-19 and Vaccine

2021

  • Clinical Characteristics and Transmission of COVID-19 in Children and Youths During 3 Waves of Outbreaks in Hong Kong. | View

Chua GT, Wong JSC, Lam I, Ho PPK, Chan WH, Yau FYS, Rosa Duque JS, Ho ACC, Siu KK, Cheung TWY, Lam DSY, Chan VCM, Lee KP, Tsui KW, Wong TW, Yau MM, Yau TY, Chan KCC, Yu MWL, Chow CK, Chiu WK, Chan KC, Wong WHS, Ho MHK, Tso WWY, Tung KTS, Wong CS, Kwok J, Leung WH, Yam JC, Wong ICK, Tam PKH, Chan GCF, Chow CB, To KKW, Lau YL, Yuen KY, Ip P, Kwan MYW. JAMA Netw Open. 2021 May 3;4(5):e218824. doi: 10.1001/jamanetworkopen.2021.8824. (PMID: 33938934)

  • Global changes to the chemotherapy service during the covid-19 pandemic. | View

Chow MC, Chambers P, Singleton G, Patel J, Cooper S, Mythen C, Bautista-González E, Chisnall G, Djellouli N, Thwaites B, Wong IC, Vindrola-Padros C. J Oncol Pharm Pract. 2021 May 13:10781552211015767. doi: 10.1177/10781552211015767. Online ahead of print. (PMID: 33983080)

  • Impact of COVID-19 Pandemic on Serum Vitamin D Level among Infants and Toddlers: An Interrupted Time Series Analysis and before-and-after Comparison. | View

Wong, RS, Tung, KTS, So, HK, Wong, WHS, Wong, SY, Tsang, HW, Tung, JYL, Chua, GT, Ho, MHK Wong, ICK, Ip, P. Nutrients. 202113, 1270. doi: 10.3390/nu13041270

  • Development of a multivariable prediction model for severe COVID-19 disease: a population-based study from Hong Kong. | View

Zhou J, Lee S, Wang X, Li Y, Wu WKK, Liu T, Cao Z, Zeng DD, Leung KSK, Wai AKC, Wong ICK, Cheung BMY, Zhang Q, Tse G. NPJ Digit Med. 2021 Apr 8;4(1):66. doi: 10.1038/s41746-021-00433-4. (PMID: 33833388)

  • Physical and mental health outcomes including behavior and attitudes in people having social contacts with COVID-19 patients. | View

Xu ZJ, Zhang DX, Xu D, Li X, Xie YJ, Sun W, Lee EKP, Yip BHK, Mo PKH, Xiao SY, Wong SYS. PlosOne. 2021 Feb 2;16(2):e0245945. doi: 10.1371/journal.pone.0245945. (PMID: 33529204) 

  • Saliva viral load better correlates with clinical and immunological profiles in children with coronavirus disease 2019 | View

Chua GT, Wong JSC, To KKW, Lam ICS, Yau FYS, Chan WH, Ho PPK, Duque JSR, Yip CCY, Ng ACK, Wong WHS, Kwong JHY, Leung KFS, Wan PT, Lam K, Wong ICK, Kwok J, Ho MHK, Chan GCF, Lau YL, Ip P, Kwan MYW. Emerg Microbes Infect. 2021 Dec; 10(1):235-241. doi: 10.1080/22221751.2021.1878937. (PMID: 33467982) 

  • COVID-19 and Health-Related Quality of Life: A Community-Based Online Survey in Hong Kong. | View

Edmond PH Choi, Bryant PH Hui, Eric YF Wan, Jojo YY Kwok, Tiffany HL Tam, Chanchan Wu. International Journal of Environmental Research and Public Health. 2021 Mar; 18(6): 3228. doi: 10.3390/ijerph18063228. (PMID: 33804725)

  • Interaction effects between angiotensin-converting enzyme inhibitors or angiotensin receptor blockers and steroid or antiviral therapies in COVID-19: A population-based study | View

Zhou J, Tse G, Lee S, Liu T, Cao Z, Zeng DD, Leung KSK, Wai AKC, Wong ICK, Cheung BMY, Zhang Q. J Med Virol. 2021 Feb 27. doi: 10.1002/jmv.26904. Online ahead of print. (PMID: 33638553))

  • Clinical outcomes of different therapeutic options for COVID-19 in two Chinese case cohorts: A propensity-score analysis. | View
    Wong CKH, Wan EYF, Luo S, Ding Y, Lau EHY, Ling P, Hu X, Lau ECH, Wong J, Zheng X, Cowling BJ, Weng J, Leung GM. EClinicalMedicine. 2021 Feb;32:100743. doi:
    10.1016/j.eclinm.2021.100743. Epub 2021 Feb 13. (PMID: 33615206)
  • Cardiovascular sequalae in uncomplicated COVID-19 survivors. | View
    Zhou M, Wong CK, Un KC, Lau YM, Lee JC, Tam FC, Lau YM, Lai WH, Tam AR, Lam YY, Pang P, Tong T, Tang M, Tse HF, Ho D, Ng MY, Chan EW, Wong ICK, Lau CP, Hung IF, Siu CW. PLoS One. 2021 Feb 11;16(2):e0246732. doi: 10.1371/journal.pone.0246732. eCollection 2021. (PMID: 33571321)
  • Comparative study of the clinical characteristics and epidemiological trend of 244 COVID-19 infected children with or without GI symptoms. | View
    Xiong XL, Wong KK, Chi SQ, Zhou AF, Tang JQ, Zhou LS, Chung PH, Chua G, Tung K, Wong I, Chui C, Li X, Kwan MY, Wong WH, Ho MH, Chan GC, Cao GQ, Li K, Ip P, Chen P, Tang ST, Tam PK. Gut. 2021 Feb;70(2):436-438 (PMID: 32430348)

 

2020

  • Development and Validation of Risk Prediction Models for COVID-19 Positivity in a Hospital Setting. | View

MY Ng, Eric YF Wan, Frank HY Wong, ST Leung, Jonan CY Lee, Thomas WY Chin, Christine SY Lo et al. International Journal of Infectious Diseases. 101(2020) 74-82; doi: 10.1016/j.ijid.2020.09.022 (PMID: 32947055)

  • Orodispersible and transmucosal alternative medications for symptom control in adults | View

Sutherland AE, Presland M, Harrop E, Carey M, Miller M, Wong ICKC. BMJ Support Palliat Care. 2020 Dec 1:bmjspcare-2020-002784. doi: 10.1136/bmjspcare-2020-002784. Online ahead of print. (PMID: 33262121)

  • COVID-19 in children across three Asian cosmopolitan regions. | View
    Chua GT, Xiong X, Choi EH, Han MS, Chang SH, Jin BL, Lee EJ, Kim BN, Kim MK, Doo K, Seo JH, Kim YJ, Kim YJ, Park JY, Suh SB, Lee H, Cho EY, Kim DH, Kim JM, Kim HY, Park SE, Lee JK, Jo DS, Cho SM, Choi JH, Jo KJ, Choe YJ, Kim KH, Chi S, Tang ST, Qin H, Zhou LS, Chen P, Wong JSC, Chan KCC, Yau FYS, Lam SY, Chow CCK, Wong TW, Chan VC, Poon GWK, Chow CB, Wong WHS, Lau YL, Chan GCF, Chui CSL, Li X, Ho MHK, Wong ICK, Tam PKH, To KKW, Kim JH, Ip P, Kwan MYW. Emerg Microbes Infect. 2020 Dec;9(1):2588-2596. doi: 10.1080/22221751.2020.1846462. (PMID: 33138739)
  • Short- and potential long-term adverse health outcomes of COVID-19: a rapid review. | View
    Leung TYM, Chan AYL, Chan EW, Chan VKY, Chui CSL, Cowling BJ, Gao L, Ge MQ, Hung IFN, Ip MSM, Ip P, Lau KK, Lau CS, Lau LKW, Leung WK, Li X, Luo H, Man KKC, Ng VWS, Siu CW, Wan EYF, Wing YK, Wong CSM, Wong KHT, Wong ICK. Emerg Microbes Infect. 2020 Dec;9(1):2190-2199. doi: 10.1080/22221751.2020.1825914. (PMID: 32940572)
  • Vulnerability and resilience in children during the COVID-19 pandemic. | View
    Tso WWY, Wong RS, Tung KTS, Rao N, Fu KW, Yam JCS, Chua GT, Chen EYH, Lee TMC, Chan SKW, Wong WHS, Xiong X, Chui CS, Li X, Wong K, Leung C, Tsang SKM, Chan GCF, Tam PKH, Chan KL, Kwan MYW, Ho MHK, Chow CB, Wong ICK, Lp P. Eur Child Adolesc Psychiatry. 2020 Nov 17:1-16. doi: 10.1007/s00787-020-01680-8. Online ahead of print. (PMID: 33205284)
  • Frequency and Distribution of Chest Radiographic Findings in COVID-19 Positive Patients. | View
    HY Wong, HY Lam, AH Fong, ST Leung, TW Chin, CS Lo, MM Liu, JC Lee, KW Chiu T Chung, EY Lee, Eric YF Wan, Ivan FN Hung, Tina PW Lam, MY Ng. Radiology. 2020 Mar 27:201160; doi: 10.1148/radiol.2020201160 (PMID: 32216717)
  • False-positive SARS-CoV-2 serology in 3 children with Kawasaki disease. I View
    To KK, Chua GT, Kwok KL, Wong JS, Au DCY, Lam YY, Wong WH, Ho MH, Chan GC, Chui CS, Li X, Tung KT, Wong RS, Tso WW, Wong IC, Wong CS, Fong CH, Chan KH, Yuen KY, Ip P, Kwan MY. Diagn Microbiol Infect Dis. 2020 Nov; 98(3):115141. doi: 10.1016/j.diagmicrobio.2020.115141. Epub 2020 Jul 17. (PMID: 32795776)
  • Clinical presentations, laboratory and radiological findings, and treatments for 11,028 COVID-19 patients: a systematic review and meta-analysis. | View
    Wong CKH, Wong JYH, Tang EHM, Au CH, Wai AKC. Sci Rep. 2020 Nov 13;10(1):19765. doi: 10.1038/s41598-020-74988-9. (PMID: 33188232)
  • Transmucosal drug administration as an alternative route in palliative and end-of-life care during the COVID-19 pandemic. | View
    Lam JKW, Cheung CCK, Chow MYT, Harrop E, Lapwood S, Barclay SIG, Wong ICK. Adv Drug Deliv Rev. 2020; 160:234-243. doi: 10.1016/j.addr.2020.10.018. Epub 2020 Nov 1. (PMID: 33137363)
  • Haematological and immunological data of Chinese children infected with coronavirus disease 2019. | View
    Xiong X, Chua GT, Chi S, Kwan MYW, Wong WHS, Zhou A, Shek CC, Tung KTS, Qin H, Wong RS, Li X, Chen P, Li S, Chui CS, Tso WWY, Ho MHK, Wong ICK, Chan GCF, Lau YL, Wong KKY, Chung PHY, Li H, Tam PKH, Tang ST, Lp P. Data Brief. 2020 Jun 30;31:105953. doi: 10.1016/j.dib.2020.105953. eCollection 2020 Aug. (PMID: 32685628)
  • Long-term outcome of short-course high-dose glucocorticoids for SARS: a 17-year follow-up in SARS survivors. | View
    Sing CW, Tan KCB, Wong ICK, Cheung BMY, Cheung CL. Clin Infect Dis. 2020 Jul 16:ciaa992. doi: 10.1093/cid/ciaa992. Online ahead of print. (PMID: 32671407)
  • Impact of National Containment Measures on Decelerating the Increase in Daily New Cases of COVID-19 in 54 Countries and 4 Epicenters of the Pandemic: Comparative Observational Study. | View
    Wong CKH, Wong JYH, Tang EHM, Au CH, Lau KTK, Wai AKC. J Med Internet Res. 2020 Jul 22;22(7):e19904. doi: 10.2196/19904. (PMID: 32658858)
  • How are family doctors serving the Hong Kong community during the COVID-19 outbreak? A survey of HKCFP members. | View
    Esther YT Yu, Will LH Leung, Samuel YS Wong, Kiki SN Liu, Eric YF Wan for the HKCFP Executive and Research Committee. Hong Kong Medical Journal. 2020: 26(3), 176-83; doi: 10.12809/hkmj208606 (PMID: 32475841)
  • Coronavirus disease 2019 (COVID-19): latest developments in potential treatments. | View
    Hon KL, Leung KKY, Leung AK, Qian SY, Chan VP, Ip P, Wong IC. Drugs Context. 2020 Jun 29;9:2020-4-15. doi: 10.7573/dic.2020-4-15. eCollection 2020. (PMID: 32655654)
  • A Comparison Between Chinese Children Infected with Coronavirus Disease-2019 and with Severe Acute Respiratory Syndrome 2003. | View
    Xiong X, Chua GT, Chi S, Kwan MYW, Sang Wong WH, Zhou A, Shek CC, Tung KTS, Qin H, Wong RS, Li X, Chen P, Li S, Chui CS, Tso WWY, Ho MHK, Wong ICK, Chan GCF, Lau YL, Wong KKY, Chung PHY, Li H, Tam PKH, Tang ST, Ip P. J Pediatr. 2020 Sep;224:30-36. doi: 10.1016/j.jpeds.2020.06.041. Epub 2020 Jun 18. (PMID: 32565097)
  • Depression and Anxiety in Hong Kong during COVID-19. | View
    Edmond PH Choi, Bryant PH HUI, Eric YF Wan. International Journal of Environmental Research and Public Health. 2020; 17(10), 3740; doi: 10.3390/ijerph17103740 (PMID: 32466251)
  • ADHD management during the COVID-19 pandemic: guidance from the European ADHD Guidelines Group. | View
    Cortese S, Asherson P, Sonuga-Barke E, Banaschewski T, Brandeis D, Buitelaar J, Coghill D, Daley D, Danckaerts M, Dittmann RW, Doepfner M, Ferrin M, Hollis C, Holtmann M, Konofal E, Lecendreux M, Santosh P, Rothenberger A, Soutullo C, Steinhausen HC, Taylor E, Van der Oord S, Wong I, Zuddas A, Simonoff E; European ADHD Guidelines Group. Lancet Child Adolesc Health. 2020 Jun;4(6):412-414. doi: 10.1016/S2352-4642(20)30110-3. Epub 2020 Apr 17. (PMID: 32311314)