Professor Susan Leung graduated from the University of Bristol, England, with a BSc Degree in Pharmacology, and obtained a PhD Degree in Pharmacology at the University of Hong Kong. Upon graduation, she was awarded the Croucher Foundation Fellowship for a postdoctoral training at Department of Pharmacology and Therapeutics at the University of British Columbia, Canada. She then returned to the University of Hong Kong for further postdoctoral training at the Department of Pharmacology. She was Research Assistant Professor and then Assistant Professor at the University of Hong Kong for the period of 2005-2014. She is now Associate Professor at the Department of Pharmacology and Pharmacy. Her research has mainly focused on the study of vascular reactivity under physiological and pathological conditions, and under the influence of different pharmacological agents.

Memberships & Editorships

Memberships:

• Executive Committee Member of Hong Kong Pharmacology Society
• Deputy Director of the Council of the Institute of Cardiovascular Sciences and Medicine
• Founding Member of Asian Society for Vascular Biology

Honours and Awards

• Visiting Lecturer, Pharmacology Department, School of Medical Sciences, Universiti Sains Malaysia 2011
• Outgoing Visitorships of Sun Yat Sen Foundation Fund for Academic Exchanges with China 2009
• Croucher Foundation Fellowship 2000-2002

• Mechanisms involved in the regulation of the vascular tone under physiological conditions and the changes associated with the development of cardiovascular diseases
• Influence of gonadal hormones on the regulation of vascular tone
• Mechanisms of actions of natural products in the vascular systems and their therapeutic potentials in the management of cardiovascular diseases

Photo of an isolated blood vessel rings in the organ chamber for measurement of isometric tension

A typical tracing of the changes in isometric tension of an isolated blood vessel ring to increasing concentrations of a relaxing agent

Staining for senescence-associated β-galactosidase (in blue) in the luminal surface of the aortic arch of male and female apolipoprotein E-knockout (Apo-E-/-) mice and their wild type counterparts (Apo-E+/+).

• Cai Y, Zhang Y, Chen H, Sun XH, Zhang P, Zhang L, Liao MY, Zhang F, Xia ZY, Man RY, Feinberg MW, Leung SWS* (2021). MicroRNA-17-3p suppresses NF-κB-mediated endothelial inflammation by targeting NIK and IKKβ binding protein. Acta Pharmacol Sin 42(12):2046-2057.
  
  [This study sheds light on potential harmful vascular effects of the agents with AMPK-activating property, including the clinically-used drugs (the antidiabetic drug metformin and lipid-lowering drug fenofibrate) and Chinese medicinal herbs (resveratrol and berberine).]
• Chen H, Vanhoutte PM, Leung SWS* (2019). Acute activation of endothelial AMPK surprisingly inhibits endothelium-dependent hyperpolarization-like relaxations in rat mesenteric arteries. Br J Pharmacol 176: 2905-2921.
  
  [This study sheds light on potential harmful vascular effects of the agents with AMPK-activating property, including the clinically-used drugs (the antidiabetic drug metformin and lipid-lowering drug fenofibrate) and Chinese medicinal herbs (resveratrol and berberine).]
• Cheng Y, Vanhoutte PM, Leung SWS* (2018). Apolipoprotein E favours the blunting by high-fat diet of prostacyclin receptor activation in the mouse aorta. Br J Pharmacol 175: 3453-3469.
  
  [The study provides evidence that iloprost may exert a favourable effect on apolipoprotein allele related cardiovascular disorders]
• Zhao Y, Vanhoutte PM, Leung SWS* (2015). α1-Adrenoceptor activation of PKC-ε causes heterologous desensitization of thromboxane receptors in the aorta of spontaneously hypertensive rats. Br J Pharmacol 172(14): 3687-3701.
  
  [This study sheds light on possible mechanisms of a crosstalk between non-prostanoid and prostanoid receptors that is modulated by hypertension. It indicates a more generalized disorder of receptor function, which contributes to the hypertensive process in vascular smooth muscle cells.]

Selected Publications

A. Peer-Reviewed Journal Publication [* Corresponding Author]

• Leung SWS, Shi Y (2022). The glycolytic process in endothelial cells and its implications. Acta Pharmacol Sin 43(2): 251-259.
• Pan HW, Seow HC, Lo JCK, Guo J, Zhu L, Leung SWS, Zhang C, Lam JKW (2022). Spray-dried and spray-freeze-dried powder formulations of an anti-interleukin-4Rα antibody for pulmonary delivery. Pharm Res 39(9):2291-2304.
• Miao L, Liu C, Cheong MS, Zhong R, Tan Y, Rengasamy KRR, Leung SWS, Cheang WS, Xiao J (2022). Exploration of natural flavones' bioactivity and bioavailability in chronic inflammation induced-type-2 diabetes mellitus. Crit Rev Food Sci Nutr 12:1-28.
• Li J, Cheng Y, Li R, Wu X, Zheng C, Shiu PH, Chan JC, Rangsinth P, Liu C, Leung SWS, Lee SM, Zhang C, Fu C, Zhang J, Cheung TM, Leung GPH (2022). Protective effects of Amauroderma rugosum on doxorubicin-induced cardiotoxicity through suppressing oxidative stress, mitochondrial dysfunction, apoptosis, and activating Akt/mTOR and Nrf2/HO-1 signaling pathways. Oxid Med Cell Longev 2022: 9266178.
• Seow HC, Liao Q, Lau ATY, Leung SWS, Yuan S, Lam JKW (2022). Dual targeting powder formulation of antiviral agent for customizable nasal and lung deposition profile through single intranasal administration. Int J Pharm 619: 121704.
• Cai Y, Zhang Y, Chen H, Sun XH, Zhang P, Zhang L, Liao MY, Zhang F, Xia ZY, Man RY, Feinberg MW, Leung SWS* (2021). MicroRNA-17-3p suppresses NF-κB-mediated endothelial inflammation by targeting NIK and IKKβ binding protein. Acta Pharmacol Sin 42(12):2046-2057.
• Li T, Shen K, Li J, Leung SWS, Zhu T, Shi Y (2021). Glomerular endothelial cells are the coordinator in the development of diabetic nephropathy. Front Med (Lausanne) 8: 655639.
• Wee CL, Mokhtar SS, Singh KKB, Yahaya S, Leung SWS, Rasool AHG (2021). Calcitriol supplementation ameliorates microvascular endothelial dysfunction in vitamin D-deficient diabetic rats by upregulating the vascular eNOS protein expression and reducing oxidative stress. Oxid Med Cell Longev 2021: 3109294.
• Leung SWS* (2021). The vascular impact of IP-TP receptor interactions. Acta Physiol 231(2): e13577.
• Zhu D, Tang Q, Yu B, Meng M, Liu W, Li J, Zhu T, Vanhoutte PM, Leung SWS, Zhang Y, Shi Y (2020). Major histocompatibility complexes are up-regulated in glomerular endothelial cells via activation of c-Jun N-terminal kinase in 5/6 nephrectomy mice. Br J Pharmacol 177: 5131-5147.
• Shi Y, Leung SWS* (2020). Long-term nitric oxide synthase inhibition prevents 17β-estradiol-induced suppression of cyclooxygenase-dependent contractions and enhancement of endothelium-dependent hyperpolarization-like relaxation in mesenteric arteries of ovariectomized rats. Eur J Pharmacol 882: 173275.
• Chen H, Vanhoutte PM, Leung SWS* (2020). Vascular adenosine monophosphate-activated protein kinase: Enhancer, brake or both? Basic Clin Pharmacol Toxicol 127: 81-91.
• Vanhoutte PM, Leung SWS* (2020). Hypoxic augmentation: The tale of a strange contraction. Basic Clin Pharmacol Toxicol 127: 59-66.
• Zhang P, Mak JCW, Man RYK, Leung SWS* (2019). Flavonoids reduces lipopolysaccharide-induced release of inflammatory mediators in human bronchial epithelial cells: Structure-activity relationship. Eur J Pharmacol 865: 172731.
• Chen H, Vanhoutte PM, Leung SWS* (2019). Acute activation of endothelial AMPK surprisingly inhibits endothelium-dependent hyperpolarization-like relaxations in rat mesenteric arteries. Br J Pharmacol 176: 2905-2921.
• Detremmerie CMS, Leung SWS, Vanhoutte PM (2018). Activation of NQO-1 mediates the augmented contractions of isolated arteries due to biased activity of soluble guanylyl cyclase in their smooth muscle. Naunyn Schmiedebergs Arch Pharmacol 391(11): 1221-1235.
• Cheng Y, Vanhoutte PM, Leung SWS* (2018). Apolipoprotein E favours the blunting by high-fat diet of prostacyclin receptor activation in the mouse aorta. Br J Pharmacol 175: 3453-3469.
• Wong ESW, Man RYK, Ng KFJ, Leung SWS*, Vanhoutte PM (2018). L-arginine and arginase products potentiate dexmedetomidine-induced contractions in the rat aorta. Anesthesiology 128(3): 564-573.
• Chen H, Man RYK, Leung SWS* (2018). PPAR-α agonists acutely inhibit Ca2+-independent PLA2 to reduce H2O2-induced contractions in aortae of spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol. 314(3): H681-H691.
• Detremmerie CM, Vanhoutte PM, Leung SWS* (2017). Biased activity of soluble guanylyl cyclase: the Janus face of thymoquinone. Acta Pharm Sin B 7(4): 401-408.
• Leung SWS*, Vanhoutte PM (2017). Endothelium-dependent hyperpolarization: age, gender and blood pressure, do they matter? Acta Physiol 219(1): 108-123.
• Jin J, Tang Q, Li Z, Zhao Z, Zhang Z, Lu L, Zhu T, Vanhoutte PM, Leung SWS, Tu R, Shi Y (2017). Prostaglandin E2 regulates renal function in C57/BL6 mouse with 5/6 nephrectomy. Life Sci 174: 68-76.
• Qiu Y, Lam JKW, Leung SWS, Liang W (2016). Delivery of RNAi therapeutics to the airways -from bench to bedside. Molecules 21(9): 1249.
• Vanhoutte PM, Zhao Y, Xu A, Leung SWS (2016). Thirty years of saying NO: sources, fate, actions, and misfortunes of the endothelium-derived vasodilator mediator. Circ Res 119(2): 375-396.
• Detremmerie CM, Chen Z, Li Z, Alkharfy K, Leung SWS, Xu A, Gao Y, Vanhoutte PM (2016). Endothelium-dependent contractions of isolated arteries to thymoquinone require biased activity of sGC with subsequent cIMP production. J Pharmacol Exp Ther 358(3): 558-568.
• Mokhtar SS, Vanhoutte PM, Leung SWS, Suppian R, Yusof MI, Rasool AH (2016). Reduced nitric oxide-mediated relaxation and endothelial nitric oxide synthase expression in the tail arteries of streptozotocin-induced diabetic rats. Eur J Pharmacol 773: 78-84.
• Mokhtar SS, Vanhoutte PM, Leung SWS, Yusof MI, Wan Sulaiman WA, Mat Saad AZ, Suppian R, Rasool AH (2016). Endothelium dependent hyperpolarization-type relaxation compensates for attenuated nitric oxide-mediated responses in subcutaneous arteries of diabetic patients. Nitric Oxide 53: 35-44.
• Zhao Y, Vanhoutte PM, Leung SWS* (2015). Vascular nitric oxide: Beyond eNOS. J Pharmacol Sci 129(2): 83-94.
• Lam JK, Chow MY, Zhang Y, Leung SWS (2015). siRNA versus miRNA as therapeutics for gene silencing. Mol Ther Nucleic Acids 4(9): e252.
• Kong BW, Man RY, Gao Y, Vanhoutte PM, Leung SWS* (2015). Reduced activity of SKCa and Na-K ATPase underlies the accelerated impairment of EDH-type relaxations in mesenteric arteries of aging spontaneously hypertensive rats. Pharmacol Res Perspect 3(3): e00150.
• Zou Q, Leung SWS*, Vanhoutte PM (2015). Transient receptor potential channel opening releases endogenous acetylcholine which contributes to endothelium-dependent relaxations induced by mild hypothermia in spontaneously hypertensive rat but not Wistar-Kyoto rat arteries. J Pharmacol Exp Ther 354(2): 121-130.
• Kong BWC, Vanhoutte PM, Man RYK, Leung SWS* (2015). 17β-estradiol potentiates endothelium-dependent nitric oxide- and hyperpolarization-mediated relaxations in blood vessels of male but not female apolipoprotein-E deficient mice. Vascul Pharmacol 71: 166-173.
• Zhao Y, Vanhoutte PM, Leung SWS* (2015). α1-Adrenoceptor activation of PKC-ε causes heterologous desensitization of thromboxane receptors in the aorta of spontaneously hypertensive rats. Br J Pharmacol 172(14): 3687-3701.
• Xu YC, Leung SWS*, Leung GPH, Man RYK (2015). Kaempferol enhances endothelium-dependent relaxation in the porcine coronary artery through activation of large-conductance Ca2+-activated K+ channels. Br J Pharmacol 172(12): 3003-3014.
• Tsui PY, Cheung CW, Lee Y, Leung SWS, Ng KF (2015). The effectiveness of low-dose desmopressin in improving hypothermia-induced impairment of primary haemostasis under influence of aspirin - a randomized controlled trial. BMC Anesthesiol 15(1): 80.
• Zhao Y, Flavahan S, Leung SWS, Xu A, Vanhoutte PM, Flavahan NA (2015). Elevated pressure causes endothelial dysfunction in mouse carotid arteries by increasing local angiotensin signaling. Am J Physiol Heart Circ Physiol 308: H358-H363.
• Gao Y, Chen Z, Leung SWS, Vanhoutte PM (2015). Hypoxic vasospasm mediated by cIMP: when soluble guanylyl cyclase turns bad. J Cardiovasc Pharmacol 65(6): 545-548.
• Chen Z, Zhang X, Ying L, Dou D, Li Y, Bai Y, Liu J, Liu L, Feng H, Yu X, Leung SWS, Vanhoutte PM, Gao Y (2014). cIMP synthesized by sGC as a mediator of hypoxic contraction of coronary arteries. Am J Physiol Heart Circ Physiol 307: H328-H336.
• Shen K, Leung SWS*, Ji L, Huang Y, Hou M, Xu A, Wang Z*, Vanhoutte PM (2014). Notoginsenoside Ft1 activates both glucocorticoid and estrogen receptors to induce endothelium-dependent, nitric oxide-mediated relaxations in rat mesenteric arteries. Biochem Pharmacol 88: 66-74.
• Zhao Y, Vanhoutte PM, Leung SWS* (2013). Endothelial nitric oxide synthase-independent release of nitric oxide in the aorta of the spontaneously hypertensive rat. J Pharmacol Exp Ther 344: 15-22.
• Yeung YY, Lee SS, Vanhoutte PM, Leung SWS* (2013). Prolonged exposure to lopinavir impairs endothelium-dependent hyperpolarization-mediated relaxation in rat mesenteric arteries. J Cardiovasc Pharmacol 62(4): 397-404.
• Lin AHY, Li RWS, Ho EYW, Leung GPH, Leung SWS, Vanhoutte PM, Man RYK (2013). Differential ligand binding affinities of human estrogen receptor-α isoforms. PLoS One 8(4): e63199.
• Yau KH, Mak JCW, Leung SWS, Yang D, Vanhoutte PM (2012). A synthetic chloride channel relaxes airway smooth muscle of the rat. PLoS One 7: e45340.
• Qu C, Leung SWS*, Vanhoutte PM, Man RYK (2012). Wy14643 improves vascular function in the aorta of the spontaneously hypertensive rat mainly by activating peroxisome proliferator-activated receptors alpha. Eur J Pharmacol 696: 101-110.
• Zou Q, Leung SWS*, Vanhoutte PM (2012). Activation of nicotinic receptors can contribute to endothelium-dependent relaxations to acetylcholine in the rat aorta. J Pharmacol Exp Ther 341: 756-763.
• Ng KF, Cheung CW, Lee Y, Leung SWS (2011). Low-dose desmopressin improves hypothermia-induced impairment of primary haemostasis in healthy volunteers. Anaesthesia 66: 999-1005.
• Zheng X, Ying L, Liu J, Dou D, He Q, Leung SWS, Man RYK, Vanhoutte PM, Gao Y (2011). Role of sulfhydryl-dependent dimerization of soluble guanylyl cyclase in relaxation of porcine coronary artery to nitric oxide. Cardiovasc Res 90: 565-572.
• Lin AHY, Leung GPH, Leung SWS, Vanhoutte PM, Man RYK (2011). Genistein enhances relaxation of the spontaneously hypertensive rat aorta by transactivation of epidermal growth factor receptor following binding to membrane estrogen receptors-α and activation of a G protein-coupled, endothelial nitric oxide synthase-dependent pathway. Pharmacol Res 63: 181-189.
• Qu C, Leung SWS, Vanhoutte PM, Man RYK (2010). Chronic inhibition of nitric oxide synthase potentiates endothelium-dependent contractions in the rat aorta by augm
enting the expression of cyclooxygenase-2. J Pharmacol Exp Ther 334: 373-380.
• Liang CF, Au ALS, Leung SWS, Ng KFJ, Feletou M, Kwan YW, Man RYK, Vanhoutte PM (2010). Endothelium-derived nitric oxide inhibits the relaxation of the porcine coronary artery to natriuretic peptides by desensitizing big conductance calcium-activated potassium channels of vascular smooth muscle. J Pharmacol Exp Ther 334: 223-231.
• Leung SWS*, Zhu DY, Man RYK (2010). Effects of the aqueous extract of Salvia Miltiorrhiza (danshen) and its magnesium tanshinoate B-enriched form on blood pressure. Phytother Res 24: 769-774.
• Teoh H, Quan A, Leung SWS*, Man RYK (2009). Vascular effects of estrone and diethylstilbestrol in porcine coronary arteries. Menopause 16: 104-109.
• Ng KF, Leung SWS, Man RYK, Vanhoutte PM (2008). Endothelium-derived hyperpolarizing factor mediated relaxations in porcine coronary arteries do not involve Gi/o proteins. Acta Pharmacol Sin 29: 1419-1424.
• Wan AKS, Leung SWS*, Zhu DY, Man RYK (2008). Vascular effects of different lipophilic components of “danshen”, a traditional Chinese medicine, in the isolated porcine coronary artery. J Nat Prod 71: 1825-1828.
• Leung SWS, Man RYK (2007). Hormones and vascular function. Introduction. Clin Exp Pharmacol Physiol 34: 799-800.
• Leung SWS, Teoh H, Keung W, Man RYK (2007). Non-genomic vascular actions of female sex hormones: physiological implications and signaling pathways. Clin Exp Pharmacol Physiol 34: 822-826.
• Xu YC, Leung SWS, Yeung DKY, Hu LH, Chen GH, Che CM, Man RYK (2007). Structure-activity relationships of flavonoids for vascular relaxation in porcine coronary artery. Phytochemistry 68: 1179-1188.
• Yeung DKY, Leung SWS*, Xu YC, Vanhoutte PM, Man RYK (2006). Puerarin, an isoflavonoid derived from Radix puerariae, potentiates endothelium-independent relaxation via the cyclic AMP pathway in porcine coronary artery. Eur J Pharmacol 552: 105-111.
• Xu YC, Yeung DKY, Man RYK, Leung SWS* (2006). Kaempferol enhances endothelium-independent and dependent relaxation in the porcine coronary artery. Mol Cell Biochem 287: 61-67.
• Leung SWS, Quan A, Lao TT, Man RYK (2006). Efficacy of different vasodilators on human umbilical arterial smooth muscle under normal and reduced oxygen conditions. Early Hum Dev 82: 457-462.
• Lee MYK, Leung SWS, Vanhoutte PM, Man RYK (2004). Genistein reduces agonist-induced contractions of porcine coronary arterial smooth muscle in a cyclic AMP-dependent manner. Eur J Pharmacol 503: 165-172.
• Quan A, Leung SWS, Lao TT, Man RYK (2003). 5-Hydroxytryptamine and thromboxane A2 as physiologic mediators of human umbilical artery closure. J Soc Gynecol Investig 10: 490-495.
• Leung SWS, Cheng X, Lim SL, Pang CCY (2003). Augmented pulmonary vascular and venous constrictions to N(G)-nitro-L-arginine methyl ester in rats with monocrotaline-induced pulmonary hypertension. Pharmacology 69: 167-170.
• Leung SWS, Huang M, Man GSK, Man RYK (2003). Detrimental vascular effects of lysophosphatidylcholine is limited by other phospholipid components of low-density lipoprotein. Mol Cell Biochem 207: 65-70.
• Cheng X, Leung SWS, Lim SL, Pang CCY (2003). Selective versus non-selective suppression of nitric oxide synthase on regional hemodynamics in rats with or without LPS-induced endotoxemia. Naunyn Schmiedebergs Arch Pharmacol 367: 372-379.
• Cheng X, Leung SWS, Lim SL, Pang CCY (2003). Attenuated arterial and venous constriction in conscious rats with streptozotocin-induced diabetes. Eur J Pharmacol 458: 299-304.
• Leung SWS, Man GSK, Man RYK (2002). Platelet-activating factor enhanced the pressor response of endothelin-1. J Cardiovasc Pharmacol 40: 528-532.
• Leung SWS, Lim SL, Pang CCY, Man RYK (2002). Use of A-192621 and IRL-2500 to unmask the mesenteric and renal vasodilator role of endothelin ET(B) receptors. J Cardiovasc Pharmacol 39: 533-543.
• Zhang H, Yu C, Jia JY, Leung SWS, Siow YL, Man RYK, Zhu DY (2002). Contents of four active components in different commercial crude drugs and preparations of danshen (Salvia miltiorrhiza). Acta Pharmacol Sin 23: 1163-1168.
• Teoh H, Quan A, Leung SWS, Man RYK (2000). Differential effects of 17beta-estradiol and testosterone on the contractile responses of porcine coronary artery. Br J Pharmacol 129: 1301-1308.
• Teoh H, Leung SWS, Quan A, Huang M, Man GSK, Man RYK (2000). Acetylcholine-mediated relaxation in rat thoracic aorta is enhanced following acute exposure to physiological concentrations of 17-estradiol. Mol Cell Biochem 207: 65-70.
• Teoh H, Leung SWS, Man RYK (1999). Short-term exposure to physiological levels of 17beta-estradiol enhances endothelium-independent relaxation in porcine coronary artery. Cardiovasc Res 42: 224-231.
• Huang M, Leung SWS, Teoh H, Man RYK (1999). Oxidation of low-density lipoprotein, phospholipid alterations and vascular function. Chin Med J (Engl) 112: 775-779.
• Leung SWS*, Teoh H, Quan A, Man RYK (1997). Endothelial dysfunction exacerbates the impairment of relaxation by lysophosphatidylcholine in porcine coronary artery. Clin Exp Pharmacol Physiol 24: 984-986.

B. Book Chapter

• Leung SWS, Gao Y, Vanhoutte PM (2017). 3',5'-cIMP as potential second messenger in the vascular wall. Handb Exp Pharmacol 238: 209-228. doi: 10.1007/164_2015_39.
• Man RYK, Leung SWS, Teoh H, Quan A, Keung W, Lee MYK (2004). Phytoestrogens and Cardiovascular Disorders. In: Pathophysiology of Cardiovascular Disease, Kluwer Academic Publishers, 513-524.

• General Research Fund, Research Grant Council of Hong Kong (2023-2025).
  The novel impact of the cardiac glycoside ouabain on angiotensin II signaling: their interplay in the development of vascular dysfunction and progression of cardiovascular complications (Principal Investigator)
• University-Industry Collaboration Programme of Innovation and Technology Funding (2020-2022)
  Development and initial validation of a novel local anesthetic drug carrying bone plate (DCBP) with diffusion optimized micro fluid channels for fracture repair manufactured by Integrated Machining Direct Metal Laser Sintering 3D printing technology (Co-Investigator)
• Health and Medical Research Fund, Food and Health Bureau of Hong Kong SAR (2017-2019)
  Paradoxical vasoconstrictor effect of thymoquinone, a natural product known to induce vasodilatation and used in humans (Principal Investigator)
• Health and Medical Research Fund, Food and Health Bureau of Hong Kong SAR (2016-2019)
  Effects of microRNA-17-3p upregulation on vascular inflammation and endothelial dysfunction caused by the human immunodeficiency virus proteins (Principal Investigator)
• Health and Medical Research Fund, Food and Health Bureau of Hong Kong SAR (2015-2018)
  Human prostacyclin receptors and endothelial dysfunction (Co-Investigator)
• General Research Fund, Research Grant Council of Hong Kong (2015-2018).
  Vasoconstrictor signals in hypoxia: role of soluble guanylyl cyclase (Principal Investigator)
• Health and Medical Research Fund, Food and Health Bureau of Hong Kong SAR (2013-2015).
  Therapeutic potential of herbal flavonoids in the management of chronic obstructive pulmonary disease (Principal Investigator)
• General Program, National Science Foundation of China (2013-2016).
  Telomere-independent Rap1 contributes to inflammation during atherosclerosis (Co-Investigator)
• General Research Fund, Research Grant Council of Hong Kong (2011-2014).
  Peroxisome Proliferator-Activated Receptors and Vascular Function (Co-Investigator)
• General Research Fund, Research Grant Council of Hong Kong (2010-2012).
  Protective effects of vitamin D on endothelial dysfunction in hypertension (Co- Investigator)
• General Research Fund, Research Grant Council of Hong Kong (2008-2011).
  Acceleration of the senescence of the endothelium by high blood pressure (Principal Investigator)
• General Research Fund, Research Grant Council of Hong Kong (2007-2010).
  Regulation of endothelial-derived hyperpolarizing factor-mediated responses in physiological and pathological conditions (Principal Investigator)
• General Research Fund, Research Grant Council of Hong Kong (2007-2010).
  Mechanism for the modulation of vascular function by flavonoids (Co-Investigator)
• General Research Fund, Research Grant Council of Hong Kong (2006-2009)
  Gender differences in the regulation of endothelium-dependent contracting factor (Co-Investigator)

Research Collaborators

• Prof MW Feinberg, Department of Medicine, Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, United State of America
• Prof Y GAO, Department of Physiology and Pathophysiology, Peking University Health Science Center, Beijing, China
• Dr JKW LAM, Department of Pharmaceutics, UCL School of Pharmacy, London, United Kingdom
• Prof SS LEE, Department of Microbiology, Chinese University of Hong Kong
• Prof KF NG, Department of Anaesthesiology, University of Hong Kong
• Prof AHG RASOOL, Pharmacology Vascular Laboratory, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia
• Dr Y Shi, Institute of Clinical Science, Zhongshan Hospital, Fudan University, Shanghai, China

Team Members

Current:

• Ms Li KONG (PhD student)
• Ms Conghui LIU (PhD student)
• Ms Jiayi DING (MMedsc student)
• Mr Qinhan LIN (MMedsc student)

Graduated:

• Ms Hui CHEN (PhD 2019)
• Ms Yuahua CHENG (PhD 2019)
• Ms Charlotte Marie Simonne DETREMMERIE (PhD 2017)
• Mr Wing Cheung Billy KONG (PhD 2011)
• Ms Chunrong HE (MPhil 2017)
• Ms Wing Yee LIU (MPhil 2014)
• Ms Carman LO (MPhil 2013)
• Mr Wanying REN (MPhil 2020)
• Ms Yuen Ting Yukiona YEUNG (MPhil 2011)
• Mr Peng ZHANG (PhD 2017)
• Ms Yingzi ZHAO (PhD 2014)
• Ms Qian ZOU (PhD 2013)

Professor Susan Leung and her research associates

Exchange Students

• Miss Siti Safiah Binti MOKHTAR, PhD Student at Universiti Sains Malaysia in Malaysia (Field Supervisor, 2011-2015)
• Mr A NEJADI, MSc in Pharmacy Student at the Faculty of Pharmaceutical Sciences of University of Copenhagen in Denmark (Supervisor, 2010-2011)

Regular Student Consultation Hours

Office